Monday, June 24, 2013

Cash for Good Behavior: Behavioral Economics for Disease Prevention


It's no surprise that as individuals, we are much more likely to do something  if there is some sort of proximate reward. We might even settle for a distal reward as long as the distance to our reward is somewhere shining on the horizon. 

An adage implies that a sign of maturity is delayed gratification. The idea that one is mature when he/she can delay getting a reward for whatever action is immediately being performed. If being comfortable with distal rewards is maturity, then what is it when we don't weigh every action by a reward? Probably altruism or... confusion... Cynicism here is unintentional. Altruism exists, but  we cannot deny that individuals make decisions based on how much benefit will be gained or how much pain can be avoided. Our decisions about life, love, work, and health are generally the ladder.  I am laying down no judgement here about the decision-making process. It would be silly if a species made decisions based on what hurt more or what was harder. I get it - we are talking about instincts here. Longevity. So how can we use this instinct to guide us towards making better choices?

Where does our action/reward reflex lead us when it comes to making decisions about maintaining our health? Take the case of flossing. Evidently the benefit of flossing every day isn't shiny enough to propel us towards adhering to oral  health recommendations for flossing....would I be more likely to do it if I got points or a free cup of tea or a dollar...yeah - probably. Yup. Definitely. I would floss more if I got something more out of the experience than a pat on the back once a year from my dentist and the vague knowledge that I maintained the health of my teeth.

Health maintenance doesn't really fit into the reward system of decision-making.  What about a prevention decision that has bigger consequences, like the decision to use a condom during sexual intercourse with a stranger? The "reward" is counter intuitive since many individuals complain that condoms make sex less pleasurable. The fact is that they make sex more safe. So here we have a risk/reward conflict. Let's complicate this conflict further. The consequences of not using condoms can lead to sexually transmitted infections (that range from uncomfortable to deadly) and unintended/unwanted pregnancy. You would think that individuals would be inclined to protect themselves...but immediate and satisfying rewards (proximate) tend to outweigh distal mediocre maintenance "rewards".  Sigh, we remain at an impasse  Unless we can change the proximate risk/reward conflict and supplement protective behavior with a proximate reward like...money. 

Cash transfers as behavior change interventions have emerged in the intersection  of education and health. Interventions have been designed attempting to keep youth enrolled in school with the intention of ultimately reducing risk behaviors like frequency of unprotected sex.  In a conditional cash transfer you must comply with a pre-specified condition (like staying enrolled in school/attending school 80% of the time) in order to be rewarded. If you don't, then no reward. An unconditional cash transfer is when you are given the reward with no specific agreement about what condition is being improved upon.

Surprisingly,  whether you say you are rewarding youth for something specific (conditional) or not (unconditional)- they are more likely to have a reduction in health risk behaviors. Girls are a bit better at this than boys. One study showed that youth enrolled in school who were in the conditional or unconditional cash transfer were 64% less likely to have contracted HIV and 76% less likely to have contracted herpes at the end of the 18 month study than those who were not receiving any sort of incentive (Baird, et. al, 2012). Hmmmm. Food for thought. Give youth a little cash for "good behavior" whether you stipulate what it is or not, they are probably more likely to protect themselves.  Noted.

There is a growing body of evidence around the effects of cash transfer programs, behavioral economics programs, economic mentorship programs, and we all know about the micro-finance programs. Many of these programs focus on education as a mediating and protective factor for health.  It is important to note that while the newer programs like cash transfers and economic mentorship are innovative, they are hard to sustain due to the fact that they are all about giving away money and not about investing for future revenue generating possibilities. One could argue that it is an investment in the health of the workforce, educated population, etc., but from a policy perspective our agendas tend to not be so mature. The policy agenda wants nay needs immediate gratification for the money spent (in order to justify expenditures) and distal rewards or delayed gratification are not a huge part of the process. A healthy educated workforce is often a reward too far off on the horizon. We can and will continue to work on this. 


-Jasmine Buttolph, MPH

Friday, March 1, 2013

PrEP: HIV prevention in pill form

HIV prevention in pill form: What is Pre-Exposure Prophylaxis? 
A huge step forward is being made in HIV prevention in the form of Pre-Exposure prophylaxis (PrEP). “What is Prep?” you might ask. This medication can prevent individuals from contracting sexually transmitted HIV with up to 90% effectiveness! So why is it that PrEP isn’t a more widely known HIV prevention technique? In part, it is because PrEP is new. The FDA approved PrEP for HIV prevention in July 2012. Shockwaves of excitement are rippling through the HIV prevention community and they look like progress. But progress doesn’t mean perfection.

A pill to add to the HIV prevention methods (PrEP)
Individuals’ varying adherence to PrEP has made efficacy equivocal and thus support for implementation is hesitant. Another reason for the hesitant implementation support is that most people simply do not really understand what PrEP is. When asked if one has heard of PrEP, most people respond by saying, “wait, is that what you take after you get pricked by a needle?” Not so much. What one takes AFTER potentially being exposed to HIV is Post-exposure prophylaxis (PEP). This has been around for occupational use since the early 1990s and for non-occupational use for almost a decade. By now, most people are familiar with PEP. What one takes before exposure to HIV is Pre-exposure prophylaxis (PrEP). The familiarity with PEP and the similarity between sounds of the Pre in PrEP and the Post in PEP seems to have slowed clear information dissemination to a wider audience. It seems trivial, but the names are too similar for most people to notice the difference. The public seems to be combining not only the names but also the meanings of the prophylaxes together. I took a small poll of some informed public health and policy colleagues and they responded with the same confusion. Unfortunate for PrEP.

PrEP is a huge step forward in prevention and the word is sluggishly and ineffectively getting around. So now for the sake of clarity it is time for a birth control analogy. PrEP is similar to daily birth control to reduce the likelihood of pregnancy as a regular prevention method for those who are sexually active and do not want to conceive. PEP is like the morning after pill; a pill taken after one has had unprotected sex. Of course the similarities of the analogy end there. According to the CDC factsheet on PrEP, the prophylaxis is actually more similar to other medications taken to prevent infection from germs or viruses like anti-malarial prophylaxis taken in malaria endemic areas.

Who should use PrEP?
PrEP is an important addition to HIV prevention interventions for individuals at high risk of contracting the virus. Who is the drug best suited for? PrEP is most effective for individuals who are frequently exposed to the virus, for example someone who is HIV negative who has an HIV positive sexual partner (a sero-discordant couple) or someone in a high prevalence area who has casual unprotected sex frequently. PrEP is not a replacement for any other prevention interventions. It should be used in addition to established interventions like condoms and couples testing and treatment. PrEP has shown potential as a gender-sensitive intervention, unlike condoms. There is a potential for women who are unable to negotiate condom use with their partners to protect themselves against exposure. Like any intervention it is not for everyone and it is not without side effects or ethical implementation issues.
Ultimately having medication that can prevent sexually transmitted HIV infection in uninfected individuals is a major advancement in the field. Both program planners and potential users have been positive about welcoming PrEP as a prevention option. Although with furrowed brows, HIV/AIDS experts note that if condoms were used more effectively and …well, just more…the need for PrEP would not be so strong. There is no way of getting around the fact that there is need for a biomedical intervention backup to patch the dangerous holes that behavioral risks create and perpetuate. Additional information about how best to implement PrEP in different populations is underway. Once it is clearer how PrEP works in the real world more can be done to increase the awareness and to target the intervention to the populations that really need it.

Jasmine Buttolph, MPH